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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCRTR1 All Species: 19.09
Human Site: S393 Identified Species: 35
UniProt: O43613 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43613 NP_001516.2 425 47536 S393 L K A P S P R S S A S H K S L
Chimpanzee Pan troglodytes XP_524646 425 47381 S393 L K A P S P R S S A S H K S L
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 H350 E Q R L D A I H S E V S V T F
Dog Lupus familis XP_544446 502 56267 S470 P K A P S P R S S A S H K S L
Cat Felis silvestris
Mouse Mus musculus P58307 416 46748 S384 L P G L G P G S S A R H K S L
Rat Rattus norvegicus P56718 416 46781 S384 L P G L G P S S S A R H K S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507023 412 46359 S381 F Q T P S S R S T S Q K S L S
Chicken Gallus gallus Q9DDN6 385 43491 H354 E Q R L D S I H P E V S A A F
Frog Xenopus laevis P70031 453 51139 T414 F R K A F L G T F S S C I K P
Zebra Danio Brachydanio rerio NP_001073337 424 48183 R393 R G E T H K Q R A R G R T S T
Tiger Blowfish Takifugu rubipres NP_001092118 426 48303 S388 L E P I S L N S L D R K P T S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120335 399 45437 L368 I S L I A H G L C Y F N S A V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789606 462 52471 D416 C C P Q P T R D S T A I T S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 25.8 78.8 N.A. 91.7 91.5 N.A. 81.8 26.5 24.5 61.1 26 N.A. 35.7 N.A. 32.9
Protein Similarity: 100 96.4 46.3 81 N.A. 93.8 93.6 N.A. 85.6 47.5 47.4 73.1 42.9 N.A. 51.7 N.A. 51.5
P-Site Identity: 100 100 6.6 93.3 N.A. 60 60 N.A. 26.6 0 6.6 6.6 20 N.A. 0 N.A. 20
P-Site Similarity: 100 100 20 93.3 N.A. 60 60 N.A. 46.6 13.3 26.6 20 33.3 N.A. 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 24 8 8 8 0 0 8 39 8 0 8 16 0 % A
% Cys: 8 8 0 0 0 0 0 0 8 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 16 0 0 8 0 8 0 0 0 0 0 % D
% Glu: 16 8 8 0 0 0 0 0 0 16 0 0 0 0 0 % E
% Phe: 16 0 0 0 8 0 0 0 8 0 8 0 0 0 16 % F
% Gly: 0 8 16 0 16 0 24 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 8 8 0 16 0 0 0 39 0 0 0 % H
% Ile: 8 0 0 16 0 0 16 0 0 0 0 8 8 0 0 % I
% Lys: 0 24 8 0 0 8 0 0 0 0 0 16 39 8 0 % K
% Leu: 39 0 8 31 0 16 0 8 8 0 0 0 0 8 39 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % N
% Pro: 8 16 16 31 8 39 0 0 8 0 0 0 8 0 8 % P
% Gln: 0 24 0 8 0 0 8 0 0 0 8 0 0 0 0 % Q
% Arg: 8 8 16 0 0 0 39 8 0 8 24 8 0 0 0 % R
% Ser: 0 8 0 0 39 16 8 54 54 16 31 16 16 54 16 % S
% Thr: 0 0 8 8 0 8 0 8 8 8 0 0 16 16 16 % T
% Val: 0 0 0 0 0 0 0 0 0 0 16 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _